Melaninandis is the pigment that provides your skin its normal color and is produced by cells called melanocytes. Melanocytes are absent in vitiligo patches. The exact reason for this is unknown. Vitiligo, but on the other side, is classified as an ‘autoimmune’ condition wherein the body’s immune system dismisses some of its own cells (melanocytes in the case of vitiligo). Aside from autoimmunity, there are several theories about the cause of vitiligo, such as ‘Genetic tendency,’ ‘Intrinsic malfunction of Melanocytes,’ ‘Neural Theory,’ ‘Oxidative Stress,’ and so forth.

Vitiligo surgery utilizes a mixture of topical agents, phototherapy (PUVA or NB-UVB), immunomodulators, and surgery to cure the condition Therapeutics are aimed at two goals: disease process stabilization (cease of ongoing depigmentation) and re-pigmentation (Formation of new pigment at the white areas). surgical schemes to re-pigment the white patches are frequently used in patients with stable disease.

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